Igfbp2<em1(cre/ERT2)Hzhu> Endonuclease-mediated Allele Detail MGI Mouse (MGI:7486103)

Igfbp2^{em1(cre/ERT2)Hzhu}
Endonuclease-mediated Allele Detail

Summary

Symbol:	Igfbp2^{em1(cre/ERT2)Hzhu}
Name:	insulin-like growth factor binding protein 2; endonuclease-mediated mutation 1, Hao Zhu
MGI ID:	MGI:7486103
Synonyms:	Igfbp2-CreER
Gene:	Igfbp2 Location: Chr1:72863662-72891633 bp, + strand Genetic Position: Chr1, 36.94 cM
Alliance:	Igfbp2^{em1(cre/ERT2)Hzhu} page

Mutation
origin

Strain of Origin:

Not Specified

Mutation
description

Allele Type:

Endonuclease-mediated (Inducible, Recombinase)

Inducer:

tamoxifen

Mutation:

Insertion

Igfbp2^{em1(cre/ERT2)Hzhu} expression driven by 1 gene

Mutation details: Using CRISPR mouse engineering, IRES-CreERT2 sequences were inserted into the 3' UTR of the Igfbp2 gene. (J:336043)

Recombinase
activity

Activity:	Tissue activity of this recombinase allele
Driver:	Igfbp2 (mouse) Summary of all recombinase alleles driven by Igfbp2. Alliance mouse Igfbp2 gene page

Find Mice (IMSR)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available Cell Lines: 0 lines available
Carrying any Igfbp2 Mutation:	22 strains or lines available

References

Original:	J:336043 Lin YH, et al., IGFBP2 expressing midlobular hepatocytes preferentially contribute to liver homeostasis and regeneration. Cell Stem Cell. 2023 May 4;30(5):665-676.e4
All:	1 reference(s)

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