About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:167305 Sims-Lucas S, et al., Fgfr1 and the IIIc isoform of Fgfr2 play critical roles in the metanephric mesenchyme mediating early inductive events in kidney development. Dev Dyn. 2011 Jan;240(1):240-9
Assay type: RNA in situ
MGI Accession ID: MGI:7488155
Gene symbol: Eya1
Gene name: EYA transcriptional coactivator and phosphatase 1
Probe: Eya1 probe
Probe preparation: Antisense labelled with digoxigenin RNA
Assay notes: Controls were littermates.
Results
Specimen 6A: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: metanephric mesenchyme Strong 6A
Specimen 6D: embryonic day 10.5; Fgfr1tm1Jpa/Fgfr1tm1Jpa, Fgfr2tm3.1Lni/Fgfr2tm3.1Lni, Tg(Pax3-cre)1Joe/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS17: metanephric mesenchyme Strong 6D Expression in this mutant is similar to controls. The mutant metanephric mesenchyme appears generally smaller.
Specimen 7A: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: metanephric mesenchyme Present 7A
Specimen 7D: embryonic day 11.5; Fgfr1tm1Jpa/Fgfr1tm1Jpa, Fgfr2tm3.1Lni/Fgfr2tm3.1Lni, Tg(Pax3-cre)1Joe/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS19: metanephric mesenchyme Present Regionally restricted 7D
Specimen 7D': embryonic day 11.5; Fgfr1tm1Jpa/Fgfr1tm1Jpa, Fgfr2tm3.1Lni/Fgfr2tm3.1Lni, Tg(Pax3-cre)1Joe/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS19: metanephric mesenchyme Present 7D'
Specimen S3A: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: nephrogenic zone Present S3A
Specimen S3B: embryonic day 12.5; Fgfr1tm1Jpa/Fgfr1tm1Jpa, Fgfr2tm3.1Lni/Fgfr2tm3.1Lni, Tg(Pax3-cre)1Joe/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS20: nephrogenic zone Present S3B In this mutant expression persisted in remnant mesenchymal tissues.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
06/12/2024
MGI 6.13 		The Jackson Laboratory