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Kcnj8tm1(cre/ERT2)Cbet
Targeted Allele Detail
Summary
Symbol: Kcnj8tm1(cre/ERT2)Cbet
Name: potassium inwardly-rectifying channel, subfamily J, member 8; targeted mutation 1, Christer Betsholtz
MGI ID: MGI:7489794
Synonyms: Kcnj8(KI)-CreERT2
Gene: Kcnj8  Location: Chr6:142510563-142517340 bp, - strand  Genetic Position: Chr6, 74.31 cM
Alliance: Kcnj8tm1(cre/ERT2)Cbet page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:325735
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Inducible, Recombinase)
Inducer:    tamoxifen
Mutation:    Insertion
 
Kcnj8tm1(cre/ERT2)Cbet expression driven by 1 gene
 
Mutation details: The T2A-CreERT2 transgene is inserted between the last amino acid and the translation termination codon in exon 3 of the Kcnj8 gene by homologous recombination. (J:325735)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Kcnj8 (mouse)
Summary of all recombinase alleles driven by Kcnj8.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Kcnj8 Mutation:  34 strains or lines available
References
Original:  J:325735 Ando K, et al., KCNJ8/ABCC9-containing K-ATP channel modulates brain vascular smooth muscle development and neurovascular coupling. Dev Cell. 2022 Jun 6;57(11):1383-1399.e7
All:  1 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
10/09/2024
MGI 6.24 		The Jackson Laboratory