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Shox2em1(cre)Zyliu
Endonuclease-mediated Allele Detail
Summary
Symbol: Shox2em1(cre)Zyliu
Name: SHOX homeobox 2; endonuclease-mediated mutation 1, Zhiyong Liu
MGI ID: MGI:7489962
Synonyms: Shox2-3*V5-P2A-Cre, Shox2*V5-Cre
Gene: Shox2  Location: Chr3:66879060-66889104 bp, - strand  Genetic Position: Chr3, 30.76 cM, cytoband E3-F1
Alliance: Shox2em1(cre)Zyliu page
Mutation
origin
Strain of Origin:  C57BL/6J
Mutation
description
Allele Type:    Endonuclease-mediated (Epitope tag, Recombinase)
Mutation:    Insertion
 
Shox2em1(cre)Zyliu expression driven by 1 gene
 
Mutation details: Using CRISPR/Cas9 technology, 3*V5-P2A-Cre was inserted into the Shox2 locus in which three V5 tags are fused at the C terminus of the gene. (J:324832)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Shox2 (mouse)
Summary of all recombinase alleles driven by Shox2.
 

Expression
In Mice Carrying this Mutation: 13 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Shox2 Mutation:  20 strains or lines available
References
Original:  J:324832 Sun Y, et al., Single-cell transcriptomic landscapes of the otic neuronal lineage at multiple early embryonic ages. Cell Rep. 2022 Mar 22;38(12):110542
All:  1 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory