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Tg(Esm1-icre/ERT2)27Rha
Transgene Detail
Summary
Symbol: Tg(Esm1-icre/ERT2)27Rha
Name: transgene insertion 27, Ralf H Adams
MGI ID: MGI:7490347
Synonyms: Esm1(BAC)iCreERT2, Esm1-iCreERT2, Esm1iCreERT2, Esm1(PAC)CreERT2
Transgene: Tg(Esm1-icre/ERT2)27Rha  Location: unknown  
Alliance: Tg(Esm1-icre/ERT2)27Rha page
Transgene
origin
Strain of Origin:  C57BL/6
Transgene
description
Transgene Type:    Transgenic (Inducible, Recombinase)
Mutation:    Insertion
 
Tg(Esm1-icre/ERT2)27Rha expression driven by 1 gene
 
Mutation details: The tamoxifen-inducible iCreERT2 was inserted into a start codon of the Esm1 gene in BAC clone RP24-560I14. Two founders were obtained of which only one (founder #27) presented transmission of the transgene to offspring. (J:246778)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Esm1 (mouse)
Summary of all recombinase alleles driven by Esm1.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:246778 Rocha SF, et al., Esm1 modulates endothelial tip cell behavior and vascular permeability by enhancing VEGF bioavailability. Circ Res. 2014 Aug 29;115(6):581-90
All:  3 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory