Tg(Rorc-mCherry,-cre/ERT2)#Litt
Transgene Detail
|
|
| Symbol: |
Tg(Rorc-mCherry,-cre/ERT2)#Litt |
| Name: |
transgene insertion, Dan R Littman |
| MGI ID: |
MGI:7493594 |
| Synonyms: |
RorgtTg(Rorgt-Cherry-CreERT2) |
| Transgene: |
Tg(Rorc-mCherry,-cre/ERT2)#Litt Location: unknown
|
| Alliance: |
Tg(Rorc-mCherry,-cre/ERT2)#Litt page
|
|
| Strain of Origin: |
Not Specified
|
|
| Transgene Type: |
|
Transgenic (Inducible, Inserted expressed sequence, Recombinase, Reporter) |
| Inducer: |
|
tamoxifen |
| Mutation: |
|
Insertion
|
| |
|
Tg(Rorc-mCherry,-cre/ERT2)#Litt expresses
1 gene
Transgene expresses:
| Organism |
Expressed Gene |
Note |
| mouse |
Rorc (MGI:104856) |
|
|
| |
|
Tg(Rorc-mCherry,-cre/ERT2)#Litt expression driven by
1 gene
Transgene expression driven by:
|
| |
|
Mutation details: The BAC clone RP24-209K20 containing mouse Rorc genomic sequence was modified such that Rorc translational start site ATG was linked to the mCherry-P2A-iCreERT2 followed by intact genomic coding and cis-regulatory sequence of Rorc gene. Line numbers were not indicated. The pound symbol (#) is used when no line is specified and/or lines are pooled.
(J:336987)
|
|
|
|
Activity: |
 Tissue activity of this recombinase allele
|
|
Driver:
|
Rorc
(mouse)
|
| |
|
|
| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
|
|
| Original: |
J:336987 Hall JA, et al., Transcription factor RORalpha enforces stability of the Th17 cell effector program by binding to a Rorc cis-regulatory element. Immunity. 2022 Nov 8;55(11):2027-2043.e9 |
| All: |
1 reference(s) |
|
Analysis Tools
