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Tg(CAG-cre)fKymm
Transgenic Allele Detail
Summary
Symbol: Tg(CAG-cre)fKymm
Name: intergenic site 54; transgene insertion f, Ken-ichi Yamamura
MGI ID: MGI:7494271
Synonyms: Creneo-f
Gene: Igs54  Location: unknown  
Alliance: Tg(CAG-cre)fKymm page
Transgene
origin
Germline Transmission:  Earliest citation of germline transmission: J:243719
Parent Cell Line:  TT2 (ES Cell)
Strain of Origin:  (C57BL/6NCrlj x CBA/JNCrlj)F1
Transgene
description
Transgene Type:    Transgenic (Recombinase)
Mutation:    Insertion
 
Tg(CAG-cre)fKymm expression driven by 1 gene
 
Mutation detailsThe allele was generated in the TT2-derived ES cell clone 71-5F2-23 by targeted replacement via RMCE in unknown Igs54 (integrated site) in the mouse locus. The original ES cell clone integrated the CAG-lox71-bsr-pA-lox511-FRT-lox2272 target lox sites. The bsr gene was replaced with the lox66-cre-pA-MC1neopA-lox2272 expression cassette through Cre-mediated recombination so that the ubiquitous CAG promoter drives Cre recombinase expression. After RMCE, ES cell clone line f was selected and generated chimera, and germline transmission was confirmed. (J:243719)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: CAG (chicken)
Summary of all recombinase alleles driven by CAG.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Igs54 Mutation:  0 strains or lines available
References
Original:  J:243719 Araki K, et al., Site-directed integration of the cre gene mediated by Cre recombinase using a combination of mutant lox sites. Nucleic Acids Res. 2002 Oct 1;30(19):e103
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
08/02/2024
MGI 6.24
The Jackson Laboratory