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Tgfb1tm1Smoc
Targeted Allele Detail
Summary
Symbol: Tgfb1tm1Smoc
Name: transforming growth factor, beta 1; targeted mutation 1, Shanghai Model Organisms Center
MGI ID: MGI:7505608
Synonyms: TGF-Beta1flox
Gene: Tgfb1  Location: Chr7:25386427-25404502 bp, + strand  Genetic Position: Chr7, 13.98 cM
Alliance: Tgfb1tm1Smoc page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:303641
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129S
Mutation
description
Allele Type:    Targeted (Conditional ready)
Mutation:    Insertion
 
Mutation detailsExon 2 was flanked by loxP sites. An FRT-flanked neomycin selection cassette was inserted downstream of the floxed exon. (J:303641)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Tgfb1 Mutation:  35 strains or lines available
References
Original:  J:303641 Song W, et al., Loss of transforming growth factor-beta1 in epithelium cells affects enamel formation in mice. Arch Oral Biol. 2018 Dec;96:146-154
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory