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Gene Expression Data
Assay Details
Assay
Reference: J:226844 Collin GB, et al., Disruption of murine Adamtsl4 results in zonular fiber detachment from the lens and in retinal pigment epithelium dedifferentiation. Hum Mol Genet. 2015 Dec 15;24(24):6958-74
Assay type: RT-PCR
MGI Accession ID: MGI:7506486
Gene symbol: Adamtsl4
Gene name: ADAMTS-like 4
Probe: Adamtsl4-pF, Adamtsl4-pR
Probe preparation: labelled with SYBR green
Assay notes: Quantitative RT-PCR. Relative expression was normalized to Actb.
Results Image: 1C
 Sample Information Bands Other Sample Information
Lane AgeStructure Size Not Specified Amount Genetic BackgroundMutant Allele(s)Sex
Lens WT P m 6 TS28: lens Present Not Specified; total RNA C57BL/6 Not Specified
Lens tvrm267 P m 6 TS28: lens Present (a) Not Specified; total RNA C57BL/6J-Adamtsl4tvrm267/Pjn Adamtsl4tvrm267/Adamtsl4tvrm267Not Specified
RPE WT P TS28: pigmented retinal epithelium Present Not Specified; total RNA C57BL/6 Not Specified
RPE tvrm267 P TS28: pigmented retinal epithelium Present (b) Not Specified; total RNA C57BL/6J-Adamtsl4tvrm267/Pjn Adamtsl4tvrm267/Adamtsl4tvrm267Not Specified
Notes:
(a) A significant change of 3.0-fold decrease in expression was noted in the lens of homozygous mutant mice.
(b) A significant change of 3.5-fold decrease in expression was noted in the RPE of homozygous mutant mice.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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06/12/2024
MGI 6.13 		The Jackson Laboratory