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Gene Expression Data
Assay Details
Assay
Reference: J:191149 Alves CH, et al., Loss of CRB2 in the mouse retina mimics human retinitis pigmentosa due to mutations in the CRB1 gene. Hum Mol Genet. 2013 Jan 1;22(1):35-50
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7506785
Gene symbol: Mpdz
Gene name: multiple PDZ domain crumbs cell polarity complex component
Antibody: anti-MUPP1 (611558)
Detection system: Secondary antibody coupled to Alexa Fluor 488
Results
Specimen 6G: postnatal month 3; Crb2tm1.1Wij/? (more )
Note: Controls could be Crb2F/F or Crb2F/+/Chx10Cre+/-.
Structure Level Pattern Image Note
TS28: retina Present Regionally restricted 6G Expression was detected in the subapical region adjacent to the outer limiting membrane.
Specimen 6H: postnatal month 3; Crb2tm1.1Wij/Crb2tm1.1Wij, Tg(Chx10-EGFP/cre,-ALPP)2Clc/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS28: retina Present Regionally restricted 6H Staining in the mutant showed disruption at the subapical region.
Specimen S1B: embryonic day 11.5; Crb2tm1.1Wij/? (more )
Note: Controls could be Crb2F/F or Crb2F/+/Chx10Cre+/-.
Structure Level Pattern Image Note
TS19: neural retinal epithelium Present Regionally restricted S1B Expression was detected in the subapical region of the neuroepithelial layer.
Specimen S1E: embryonic day 11.5; Crb2tm1.1Wij/Crb2tm1.1Wij, Tg(Chx10-EGFP/cre,-ALPP)2Clc/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS19: neural retinal epithelium Present Regionally restricted S1E , S1H Expression was detected in the subapical region of the neuroepithelial layer.
Specimen S2B: postnatal day 3; Crb2tm1.1Wij/? (more )
Note: Controls could be Crb2F/F or Crb2F/+/Chx10Cre+/-. Double labeled: green - Mpdz; red - Patj (assay MGI:7507063).
Structure Level Pattern Image Note
TS27: retina Present Regionally restricted S2C , S2B Immunostaining in the subapical region co-stained with Patj.
Specimen S2E: postnatal day 3; Crb2tm1.1Wij/Crb2tm1.1Wij, Tg(Chx10-EGFP/cre,-ALPP)2Clc/0 (more )
Note: Conditional mutant. Double labeled: green - Mpdz; red - Patj (assay MGI:7507063).
Structure Level Pattern Image Note
TS27: retina Present Regionally restricted S2F , S2E Expression was detected in the subapical region.
TS27: neural retina Present Regionally restricted S2F , S2E Expression was detected close to the periphery in rosettes and half-rosettes in the neuroepithelial layer.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/17/2024
MGI 6.24 		The Jackson Laboratory