About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:191149 Alves CH, et al., Loss of CRB2 in the mouse retina mimics human retinitis pigmentosa due to mutations in the CRB1 gene. Hum Mol Genet. 2013 Jan 1;22(1):35-50
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7506785
Gene symbol: Mpdz
Gene name: multiple PDZ domain crumbs cell polarity complex component
Antibody: anti-MUPP1 (611558)
Detection system: Secondary antibody coupled to Alexa Fluor 488
Results
Specimen 6G: postnatal month 3; Crb2tm1.1Wij/? (more )
Note: Controls could be Crb2F/F or Crb2F/+/Chx10Cre+/-.
Structure Level Pattern Image Note
TS28: retina Present Regionally restricted 6G Expression was detected in the subapical region adjacent to the outer limiting membrane.
Specimen 6H: postnatal month 3; Crb2tm1.1Wij/Crb2tm1.1Wij, Tg(Chx10-EGFP/cre,-ALPP)2Clc/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS28: retina Present Regionally restricted 6H Staining in the mutant showed disruption at the subapical region.
Specimen S1B: embryonic day 11.5; Crb2tm1.1Wij/? (more )
Note: Controls could be Crb2F/F or Crb2F/+/Chx10Cre+/-.
Structure Level Pattern Image Note
TS19: neural retinal epithelium Present Regionally restricted S1B Expression was detected in the subapical region of the neuroepithelial layer.
Specimen S1E: embryonic day 11.5; Crb2tm1.1Wij/Crb2tm1.1Wij, Tg(Chx10-EGFP/cre,-ALPP)2Clc/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS19: neural retinal epithelium Present Regionally restricted S1E , S1H Expression was detected in the subapical region of the neuroepithelial layer.
Specimen S2B: postnatal day 3; Crb2tm1.1Wij/? (more )
Note: Controls could be Crb2F/F or Crb2F/+/Chx10Cre+/-. Double labeled: green - Mpdz; red - Patj (assay MGI:7507063).
Structure Level Pattern Image Note
TS27: retina Present Regionally restricted S2C , S2B Immunostaining in the subapical region co-stained with Patj.
Specimen S2E: postnatal day 3; Crb2tm1.1Wij/Crb2tm1.1Wij, Tg(Chx10-EGFP/cre,-ALPP)2Clc/0 (more )
Note: Conditional mutant. Double labeled: green - Mpdz; red - Patj (assay MGI:7507063).
Structure Level Pattern Image Note
TS27: retina Present Regionally restricted S2F , S2E Expression was detected in the subapical region.
TS27: neural retina Present Regionally restricted S2F , S2E Expression was detected close to the periphery in rosettes and half-rosettes in the neuroepithelial layer.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
06/12/2024
MGI 6.13 		The Jackson Laboratory