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Slc12a1tm1(cre/ERT2)Jlo
Targeted Allele Detail
Summary
Symbol: Slc12a1tm1(cre/ERT2)Jlo
Name: solute carrier family 12, member 1; targeted mutation 1, Johannes Loffing
MGI ID: MGI:7512819
Synonyms: Slc12a1-CreERT2, Slc12a1 tm(cre/ERT2)Jlo
Gene: Slc12a1  Location: Chr2:124994430-125071922 bp, + strand  Genetic Position: Chr2, 61.23 cM
Alliance: Slc12a1tm1(cre/ERT2)Jlo page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:338443
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Inducible, Recombinase)
Inducer:    tamoxifen
Mutation:    Insertion
 
Slc12a1tm1(cre/ERT2)Jlo expression driven by 1 gene
 
Mutation details: The IRES-Cre/ERT2 sequence was inserted by homologous recombination into the 3'-UTR of the 27th exon of the SLC12a1 gene immediately after the stop codon. (J:338443)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Slc12a1 (mouse)
Summary of all recombinase alleles driven by Slc12a1.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Slc12a1 Mutation:  55 strains or lines available
References
Original:  J:338443 Bourqui L, et al., A novel mouse model for an inducible gene modification in the renal thick ascending limb. Am J Physiol Renal Physiol. 2023 May 1;324(5):F446-F460
All:  1 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
10/09/2024
MGI 6.24 		The Jackson Laboratory