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Dcxem1(cre/ERT2)Jjan
Endonuclease-mediated Allele Detail
Summary
Symbol: Dcxem1(cre/ERT2)Jjan
Name: doublecortin; endonuclease-mediated mutation 1, Joanna Jankowsky
MGI ID: MGI:7513054
Gene: Dcx  Location: ChrX:142638838-142716307 bp, - strand  Genetic Position: ChrX, 64.89 cM
Alliance: Dcxem1(cre/ERT2)Jjan page
Mutation
origin
Strain of Origin:  C57BL/6J
Mutation
description
Allele Type:    Endonuclease-mediated (Recombinase)
Mutation:    Insertion
 
Dcxem1(cre/ERT2)Jjan expression driven by 1 gene
 
Mutation details: CRISPR/cas9 genome editing is used to insert an in-frame T2A ribosome skipping sequence and Cre recombinase/ERT2 fusion immediately following the final M366 residue in exon 7. The inserted sequence is not expected to affect expression of Dcx. (J:343514)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Dcx (mouse)
Summary of all recombinase alleles driven by Dcx.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Dcx Mutation:  20 strains or lines available
References
Original:  J:343514 Perez GA, et al., Generation of a Dcx-CreER(T2) knock-in mouse for genetic manipulation of newborn neurons. Genesis. 2023 Dec 16;:e23584
All:  1 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory