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Gene Expression Data
Assay Details
Assay
Reference: J:199486 Watanabe Y, et al., Sox10 and Itgb1 interaction in enteric neural crest cell migration. Dev Biol. 2013 Jul 1;379(1):92-106
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7513919
Gene symbol: Itgb1
Gene name: integrin beta 1 (fibronectin receptor beta)
Antibody: Anti-Integrin beta1 (clone MB1.2, MAB1997)
Detection system: Secondary antibody
Results
Specimen 7D beta1-het: embryonic day 17.5; Gt(ROSA)26Sortm1(EYFP)Cos/Gt(ROSA)26Sor+, Itgb1tm1Ref/Itgb1+, Tg(PLAT-cre)116Sdu/0 (more )
Note: Conditional mutant. Double labeled: red - Itgb1; green - Sox10 (assay MGI:7513917).
Structure Cell Type Level Pattern Image Note
TS25: enteric nervous system enteric neuron Present 7D beta1-HT merge , 7D beta1-HT beta1 Expressed at a lower level in enteric ganglia compared to muscle, detected in Sox10+ cells.
TS25: gut enteric neuron Present 7D beta1-HT merge , 7D beta1-HT beta1 Expressed at a lower level in enteric ganglia compared to muscle, detected in Sox10+ cells.
TS25: intestine smooth muscle Present 7D beta1-HT merge , 7D beta1-HT beta1

Specimen 7D DH: embryonic day 17.5; Gt(ROSA)26Sortm1(EYFP)Cos/Gt(ROSA)26Sor+, Itgb1tm1Ref/Itgb1+, Sox10tm1Weg/Sox10+, Tg(PLAT-cre)116Sdu/0 (more )
Note: Conditional mutant. Double labeled: red - Itgb1; green - Sox10 (assay MGI:7513917).
Structure Cell Type Level Pattern Image Note
TS25: enteric nervous system enteric neuron Present 7D DH beta1 , 7D DH merge Expressed at a lower level in enteric ganglia compared to muscle, detected in Sox10+ cells.
TS25: gut enteric neuron Present 7D DH beta1 , 7D DH merge Expressed at a lower level in enteric ganglia compared to muscle, detected in Sox10+ cells.
TS25: intestine smooth muscle Present 7D DH beta1 , 7D DH merge

Specimen not shown: embryonic day 17.5; Gt(ROSA)26Sortm1(EYFP)Cos/Gt(ROSA)26Sor+, Itgb1tm1Ref/Itgb1tm2Ref, Tg(PLAT-cre)116Sdu/0 (more )
Note: Conditional mutant. Double labeled: red - Itgb1; green - Sox10 (assay MGI:7513917).
Structure Cell Type Level Pattern Image Note
TS25: enteric nervous system enteric neuron Absent
TS25: gut enteric neuron Absent

Specimen not shown: embryonic day 17.5; Gt(ROSA)26Sortm1(EYFP)Cos/Gt(ROSA)26Sor+, Itgb1tm1Ref/Itgb1tm2Ref, Sox10tm1Weg/Sox10+, Tg(PLAT-cre)116Sdu/0 (more )
Note: Conditional mutant. Double labeled: red - Itgb1; green - Sox10 (assay MGI:7513917).
Structure Cell Type Level Pattern Image Note
TS25: enteric nervous system enteric neuron Absent
TS25: gut enteric neuron Absent

Specimen not shown: embryonic day 17.5 (more )
Note: Double labeled: red - Itgb1; green - Sox10 (assay MGI:7513917).
Structure Cell Type Level Pattern Image Note
TS25: enteric nervous system enteric neuron Present Expressed at a lower level in enteric ganglia compared to muscle, detected in Sox10+ cells.
TS25: gut enteric neuron Present Expressed at a lower level in enteric ganglia compared to muscle, detected in Sox10+ cells.

Specimen not shown: embryonic day 17.5; Gt(ROSA)26Sortm1(EYFP)Cos/Gt(ROSA)26Sor+, Itgb1tm1Ref/Itgb1+, Sox10tm1Weg/Sox10+ (more )
Note: Double labeled: red - Itgb1; green - Sox10 (assay MGI:7513917).
Structure Cell Type Level Pattern Image Note
TS25: enteric nervous system enteric neuron Present Expressed at a lower level in enteric ganglia compared to muscle, detected in Sox10+ cells.
TS25: gut enteric neuron Present Expressed at a lower level in enteric ganglia compared to muscle, detected in Sox10+ cells.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
06/12/2024
MGI 6.13
The Jackson Laboratory