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Amhr2em1(icre)Fjd
Endonuclease-mediated Allele Detail
Summary
Symbol: Amhr2em1(icre)Fjd
Name: anti-Mullerian hormone type 2 receptor; endonuclease-mediated mutation 1, Franco J DeMayo
MGI ID: MGI:7513976
Synonyms: Amhr2-iCre(Fjd)
Gene: Amhr2  Location: Chr15:102353802-102363068 bp, + strand  Genetic Position: Chr15, 57.58 cM
Alliance: Amhr2em1(icre)Fjd page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:335505
Parent Cell Line:  G4 (ES Cell)
Strain of Origin:  (129S6/SvEvTac x C57BL/6NCrl)F1
Mutation
description
Allele Type:    Endonuclease-mediated (Null/knockout, Recombinase)
Mutations:    Insertion, Intragenic deletion
 
Amhr2em1(icre)Fjd expression driven by 1 gene
 
Mutation details: Using CRISPR/Cas9 technology, the codon improved iCre recombinase open reading frame (ORF) and Sv40 polyadenylation sequence replaced the genomic sequence immediately downstream of the start codon in exon 1 of the Amhr2. (J:335505)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Amhr2 (mouse)
Summary of all recombinase alleles driven by Amhr2.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Amhr2 Mutation:  29 strains or lines available
References
Original:  J:335505 Dickson MJ, et al., iCre recombinase expressed in the anti-Mullerian hormone receptor 2 gene causes global genetic modification in the mouse. Biol Reprod. 2023 Apr 11;108(4):575-583
All:  1 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory