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Trpa1tm1.1(cre)Kzim
Targeted Allele Detail
Summary
Symbol: Trpa1tm1.1(cre)Kzim
Name: transient receptor potential cation channel, subfamily A, member 1; targeted mutation 1.1, Katharina Zimmermann
MGI ID: MGI:7514628
Synonyms: TRPA1-IC
Gene: Trpa1  Location: Chr1:14942872-14989086 bp, - strand  Genetic Position: Chr1, 4.5 cM
Alliance: Trpa1tm1.1(cre)Kzim page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:338729
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Recombinase)
Mutation:    Insertion
 
Trpa1tm1.1(cre)Kzim expression driven by 1 gene
 
Mutation details: The targeting construct inserted an IRES-Cre-pgk promoterdriven Flp recombination target (FRT)neomycin (neo)FRT cassette downstream of the stop codon in the exon 27of the Trpa1 gene by homologous recombination in ES cells. The FRT flanked neo selection cassette was removed by FLP-deleter mice. (J:338729)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Trpa1 (mouse)
Summary of all recombinase alleles driven by Trpa1.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Trpa1 Mutation:  94 strains or lines available
References
Original:  J:338729 Bernal L, et al., Odontoblast TRPC5 channels signal cold pain in teeth. Sci Adv. 2021 Mar;7(13)
All:  1 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory