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Arr3tm1.1(cre/ERT2)Eye
Targeted Allele Detail
Summary
Symbol: Arr3tm1.1(cre/ERT2)Eye
Name: arrestin 3, retinal; targeted mutation 1.1, Stephen H Tsang
MGI ID: MGI:7514881
Synonyms: Arr32ACreERT2
Gene: Arr3  Location: ChrX:99649103-99662099 bp, + strand  Genetic Position: ChrX, 43.72 cM, cytoband C2
Alliance: Arr3tm1.1(cre/ERT2)Eye page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:338407
Parent Cell Line:  KV1 (ES Cell)
Strain of Origin:  (C57BL/6J x 129S6/SvEvTac)F1
Mutation
description
Allele Type:    Targeted (Inducible, Recombinase)
Inducer:    tamoxifen
Mutation:    Insertion
 
Arr3tm1.1(cre/ERT2)Eye expression driven by 1 gene
 
Mutation details: A 2A peptide-CreERT2 and an FRT-flanked neomycin cassette introduced the translation STOP codon (TAG) of the Arr3 gene by homologous recombination in the ES cells. Male chimeras were bred to ACTB-FLPe females for germline transmission and neomycin cassette removal. (J:338407)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Arr3 (mouse)
Summary of all recombinase alleles driven by Arr3.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Arr3 Mutation:  11 strains or lines available
References
Original:  J:338407 Wang NK, et al., Spatiotemporal control of genome engineering in cone photoreceptors. Cell Biosci. 2023 Jun 28;13(1):119
All:  1 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory