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Nrltm1(cre/ERT2)Jpea
Targeted Allele Detail
Summary
Symbol: Nrltm1(cre/ERT2)Jpea
Name: neural retina leucine zipper gene; targeted mutation 1, Jillian N Pearring
MGI ID: MGI:7514918
Synonyms: Nrl:CreERT2
Gene: Nrl  Location: Chr14:55756973-55762438 bp, - strand  Genetic Position: Chr14, 28.19 cM
Alliance: Nrltm1(cre/ERT2)Jpea page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:338794
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Inducible, Recombinase)
Inducer:    tamoxifen
Mutation:    Insertion
 
Nrltm1(cre/ERT2)Jpea expression driven by 1 gene
 
Mutation details: An internal ribosome entry site (IRES), a tamoxifen-inducible CreERT2, and a neomycin cassette were inserted behind the stop codon for the Nrl gene within exon 4 by homologous recombination in the ES cells. (J:338794)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Nrl (mouse)
Summary of all recombinase alleles driven by Nrl.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Nrl Mutation:  18 strains or lines available
References
Original:  J:338794 Thorson MT, et al., Nrl:CreERT2 mouse model to induce mosaic gene expression in rod photoreceptors. Front Mol Neurosci. 2023;16:1161127
All:  1 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory