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Gt(ROSA)26Sortm1(CAG-flp)Htng
Targeted Allele Detail
Summary
Symbol: Gt(ROSA)26Sortm1(CAG-flp)Htng
Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 1, Hiroki Taniguchi
MGI ID: MGI:7514974
Synonyms: FLEX-Flp
Gene: Gt(ROSA)26Sor  Location: Chr6:113044389-113054205 bp, - strand  Genetic Position: Chr6, 52.73 cM
Alliance: Gt(ROSA)26Sortm1(CAG-flp)Htng page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:338678
Parent Cell Line:  v6.5 (ES Cell)
Strain of Origin:  (C57BL/6 x 129S4/SvJae)F1
Mutation
description
Allele Type:    Targeted (Recombinase)
Mutation:    Insertion
 
Gt(ROSA)26Sortm1(CAG-flp)Htng expression driven by 1 gene
 
Mutation details: A CAG promoter and a FLEX-Flp cassette were inserted into the Gt(ROSA)26Sor locus by homologous recombination in ES cells. (J:338678)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: CAG (chicken)
Summary of all recombinase alleles driven by CAG.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Gt(ROSA)26Sor Mutation:  993 strains or lines available
References
Original:  J:338678 Hayano Y, et al., IgSF11 homophilic adhesion proteins promote layer-specific synaptic assembly of the cortical interneuron subtype. Sci Adv. 2021 Jul;7(29)
All:  1 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory