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Car4em1(cre/ERT2)Bzsh
Endonuclease-mediated Allele Detail
Summary
Symbol: Car4em1(cre/ERT2)Bzsh
Name: carbonic anhydrase 4; endonuclease-mediated mutation 1, Bin Zhou
MGI ID: MGI:7514993
Synonyms: Car4-RSR-CreER
Gene: Car4  Location: Chr11:84848612-84856870 bp, + strand  Genetic Position: Chr11, 51.34 cM
Alliance: Car4em1(cre/ERT2)Bzsh page
Mutation
origin
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Endonuclease-mediated (Conditional ready, Inducible, Recombinase)
Inducer:    tamoxifen
Mutation:    Insertion
 
Car4em1(cre/ERT2)Bzsh expression driven by 1 gene
 
Mutation details: The rox-STOP-rox, CreERT2, WPRE, and polyA cassettes were placed into the exon1 of the Car4 gene via CRISPR/Cas9-mediated homologous recombination. (J:338265)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Car4 (mouse)
Summary of all recombinase alleles driven by Car4.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Car4 Mutation:  25 strains or lines available
References
Original:  J:338265 Zhang Z, et al., Generation of Plvap-CreER and Car4-CreER for genetic targeting of distinct lung capillary populations. J Genet Genomics. 2022 Dec;49(12):1093-1100
All:  1 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory