Gt(ROSA)26Sortm1(CAG-dreo)Hshu
Targeted Allele Detail
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| Symbol: |
Gt(ROSA)26Sortm1(CAG-dreo)Hshu |
| Name: |
gene trap ROSA 26, Philippe Soriano; targeted mutation 1, Hsien-Sung Huang |
| MGI ID: |
MGI:7516274 |
| Synonyms: |
tdTomato-Dre |
| Gene: |
Gt(ROSA)26Sor Location: Chr6:113044389-113054205 bp, - strand Genetic Position: Chr6, 52.73 cM
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| Alliance: |
Gt(ROSA)26Sortm1(CAG-dreo)Hshu page
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| Germline Transmission: |
Earliest citation of germline transmission:
J:338445
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| Parent Cell Line: |
JM8A1.N3 (ES Cell)
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| Strain of Origin: |
C57BL/6N-Atm1Brd
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| Allele Type: |
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Targeted (Conditional ready, Recombinase, Reporter) |
| Mutation: |
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Insertion
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Gt(ROSA)26Sortm1(CAG-dreo)Hshu expression driven by
1 gene
Knock-in expression driven by:
| Organism |
Driver Gene |
Note |
| chicken |
CAG |
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Mutation details: The targeting vector inserted the CAG promoter, FRT flanked 3XpA, loxP flanked 3XpA, tdTomato-p2A-DreO, and Neo into the Gt(ROSA)26Sor gene via homologous recombination in embryonic stem cells. The removal of both STOP sequences by Flp and Cre recombinase is required to express the tdTomato and DreO recombinase.
(J:338445)
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Activity: |
 Tissue activity of this recombinase allele
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Driver:
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CAG
(chicken)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Carrying any Gt(ROSA)26Sor Mutation: |
993 strains or lines available
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| Original: |
J:338445 Huang DF, et al., An intersectional genetic approach for simultaneous cell type-specific labelling and gene knockout in the mouse. Development. 2023 Feb 15;150(4):dev201198 |
| All: |
1 reference(s) |
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Analysis Tools
