Tg(Tff2-Hbegf,-cre/ERT2)#Tcw
Transgene Detail
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Symbol: |
Tg(Tff2-Hbegf,-cre/ERT2)#Tcw |
Name: |
transgene insertion, Timothy C Wang |
MGI ID: |
MGI:7520440 |
Synonyms: |
Tff2-DTR-CreERT2 |
Transgene: |
Tg(Tff2-Hbegf,-cre/ERT2)#Tcw Location: unknown
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Alliance: |
Tg(Tff2-Hbegf,-cre/ERT2)#Tcw page
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Strain of Origin: |
CBA x C57BL/6J
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Transgene Type: |
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Transgenic (Inducible, Inserted expressed sequence, Recombinase) |
Inducer: |
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tamoxifen |
Mutation: |
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Insertion
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Tg(Tff2-Hbegf,-cre/ERT2)#Tcw expresses
1 gene
Transgene expresses:
Organism |
Expressed Gene |
Note |
Not Specified |
Hbegf |
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Tg(Tff2-Hbegf,-cre/ERT2)#Tcw expression driven by
1 gene
Transgene expression driven by:
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Mutation details: Using recombineering methods, the DTR-CreERT2-FrtNeoFrt cassette was inserted at the ATG codon in exon 1 of the Tff2 gene in the BAC RP24-335C16. The modified BAC construct was injected into fertilized CBA x C57BL/6J oocytes. The modified BAC construct was injected into fertilized CBA x C57BL/6J oocytes. The pound symbol (#) is used when no line is specified and/or lines are pooled.
(J:338908)
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Activity: |
Tissue activity of this recombinase allele
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Driver:
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Tff2
(mouse)
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Original: |
J:338908 Jiang Z, et al., Tff2 defines transit-amplifying pancreatic acinar progenitors that lack regenerative potential and are protective against Kras-driven carcinogenesis. Cell Stem Cell. 2023 Aug 3;30(8):1091-1109.e7 |
All: |
1 reference(s) |
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