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Tg(Tff2-Hbegf,-cre/ERT2)#Tcw
Transgene Detail
Summary
Symbol: Tg(Tff2-Hbegf,-cre/ERT2)#Tcw
Name: transgene insertion, Timothy C Wang
MGI ID: MGI:7520440
Synonyms: Tff2-DTR-CreERT2
Transgene: Tg(Tff2-Hbegf,-cre/ERT2)#Tcw  Location: unknown  
Alliance: Tg(Tff2-Hbegf,-cre/ERT2)#Tcw page
Transgene
origin
Strain of Origin:  CBA x C57BL/6J
Transgene
description
Transgene Type:    Transgenic (Inducible, Inserted expressed sequence, Recombinase)
Inducer:    tamoxifen
Mutation:    Insertion
 
Tg(Tff2-Hbegf,-cre/ERT2)#Tcw expresses 1 gene
 
Tg(Tff2-Hbegf,-cre/ERT2)#Tcw expression driven by 1 gene
 
Mutation detailsUsing recombineering methods, the DTR-CreERT2-FrtNeoFrt cassette was inserted at the ATG codon in exon 1 of the Tff2 gene in the BAC RP24-335C16. The modified BAC construct was injected into fertilized CBA x C57BL/6J oocytes. The modified BAC construct was injected into fertilized CBA x C57BL/6J oocytes. The pound symbol (#) is used when no line is specified and/or lines are pooled. (J:338908)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Tff2 (mouse)
Summary of all recombinase alleles driven by Tff2.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:338908 Jiang Z, et al., Tff2 defines transit-amplifying pancreatic acinar progenitors that lack regenerative potential and are protective against Kras-driven carcinogenesis. Cell Stem Cell. 2023 Aug 3;30(8):1091-1109.e7
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory