Gt(ROSA)26Sorem1(CAG-Ncre/vvd*,-vvd*/Ccre)Larc
Endonuclease-mediated Allele Detail
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| Symbol: |
Gt(ROSA)26Sorem1(CAG-Ncre/vvd*,-vvd*/Ccre)Larc |
| Name: |
gene trap ROSA 26, Philippe Soriano; endonuclease-mediated mutation 1, Tomoji Mashimo |
| MGI ID: |
MGI:7523854 |
| Synonyms: |
PA-Cre KI |
| Gene: |
Gt(ROSA)26Sor Location: Chr6:113044389-113054205 bp, - strand Genetic Position: Chr6, 52.73 cM
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| Alliance: |
Gt(ROSA)26Sorem1(CAG-Ncre/vvd*,-vvd*/Ccre)Larc page
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| Allele Type: |
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Endonuclease-mediated (Inducible, Recombinase) |
| Inducer: |
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blue light exposure |
| Mutation: |
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Insertion
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Gt(ROSA)26Sorem1(CAG-Ncre/vvd*,-vvd*/Ccre)Larc expression driven by
1 gene
Knock-in expression driven by:
| Organism |
Driver Gene |
Note |
| chicken |
CAG |
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Mutation details: A 7.0 kb PA-Cre expression plasmid under the control of the CAG promoter was introduced at the Gt(ROSA)26Sor locus using the CRISPR/Cas9 system. PA-Cre consists of a split Cre (59/60) with each fragment complemented with nMag or pMag (respectively) and a nuclear localization sequence (NLS) (CreN59-nMag-NLS and NLS-pMag-CreC60), separated by P2A self-cleaving peptide sequence (2A). The nMag and pMag are part of Magnets protein derived from the fragments of photoreceptor gene product Vivid (VVD) from a filamentous fungi Neurospora crassa.
(J:339595)
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Activity: |
 Tissue activity of this recombinase allele
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Driver:
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CAG
(chicken)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Carrying any Gt(ROSA)26Sor Mutation: |
993 strains or lines available
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| Original: |
J:339595 Yoshimi K, et al., Photoactivatable Cre knock-in mice for spatiotemporal control of genetic engineering in vivo. Lab Invest. 2021 Jan;101(1):125-135 |
| All: |
1 reference(s) |
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Analysis Tools
