Rbpms<em1(cre/ERT2)Gan> Endonuclease-mediated Allele Detail MGI Mouse (MGI:7523861)

Rbpms^{em1(cre/ERT2)Gan}
Endonuclease-mediated Allele Detail

Summary

Symbol:	Rbpms^{em1(cre/ERT2)Gan}
Name:	RNA binding protein gene with multiple splicing; endonuclease-mediated mutation 1, Lin Gan
MGI ID:	MGI:7523861
Synonyms:	Rbpms-CreER^T2
Gene:	Rbpms Location: Chr8:34272671-34419891 bp, - strand Genetic Position: Chr8, 20.85 cM
Alliance:	Rbpms^{em1(cre/ERT2)Gan} page

Mutation
origin

Strain of Origin:

C57BL/6J

Mutation
description

Allele Type:

Endonuclease-mediated (Inducible, Recombinase)

Inducer:

tamoxifen

Mutation:

Insertion

Rbpms^{em1(cre/ERT2)Gan} expression driven by 1 gene

Mutation details: Using CRISPR/Cas9 technology, a P2A-CreERT2 gene cassette was inserted in-frame fusion to the the C-terminus of the Rbpms gene. (J:339190)

Recombinase
activity

Activity:	Tissue activity of this recombinase allele
Driver:	Rbpms (mouse) Summary of all recombinase alleles driven by Rbpms. Alliance mouse Rbpms gene page

Find Mice (IMSR)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available Cell Lines: 0 lines available
Carrying any Rbpms Mutation:	493 strains or lines available

References

Original:	J:339190 Guo L, et al., Inducible Rbpms-CreER(T2) Mouse Line for Studying Gene Function in Retinal Ganglion Cell Physiology and Disease. Cells. 2023 Jul 27;12(15)
All:	1 reference(s)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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