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Oca2tm1(cre/ERT2)Mymi
Targeted Allele Detail
Summary
Symbol: Oca2tm1(cre/ERT2)Mymi
Name: oculocutaneous albinism II; targeted mutation 1, Mayumi Ito
MGI ID: MGI:7526532
Synonyms: Oca2creER
Gene: Oca2  Location: Chr7:55889508-56186266 bp, + strand  Genetic Position: Chr7, 33.44 cM
Alliance: Oca2tm1(cre/ERT2)Mymi page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:340038
Parent Cell Line:  Other (see notes) (ES Cell)
Strain of Origin:  C57BL/6J
Mutation
description
Allele Type:    Targeted (Inducible, Recombinase)
Inducer:    tamoxifen
Mutation:    Insertion
 
Oca2tm1(cre/ERT2)Mymi expression driven by 1 gene
 
Mutation details: The targeting construct was designed to insert p2A-Cre/ERT2 followed by a frt-flanked neo-selection cassette into the mouse Oca2 gene locus. (J:340038)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Oca2 (mouse)
Summary of all recombinase alleles driven by Oca2.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Oca2 Mutation:  70 strains or lines available
Notes
MK6 (C57BL/6J) ES cells were used.
References
Original:  J:340038 Sun Q, et al., Dedifferentiation maintains melanocyte stem cells in a dynamic niche. Nature. 2023 Apr;616(7958):774-782
All:  1 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory