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Gene Expression Data
Assay Details
Assay
Reference: J:140027 Zou D, et al., Eya1 gene dosage critically affects the development of sensory epithelia in the mammalian inner ear. Hum Mol Genet. 2008 Nov 1;17(21):3340-56
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7526721
Gene symbol: Sox2
Gene name: SRY (sex determining region Y)-box 2
Antibody: anti-Sox2
Detection system: horseradish peroxidase
Results
Specimen 4C: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: semicircular canal epithelium Present 4C Showed overlapping pattern with Eya1.
TS21: utricle epithelium Present 4C Showed overlapping pattern with Eya1.

Specimen 4G: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: cochlea epithelium Strong Regionally restricted 4G Expressed strongly in the future organ of Corti and extended weakly into adjacent great epithelial ridge region.

Specimen 4M: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: cochlea epithelium Present Regionally restricted 4M Expressed in the great epithelial ridge and the future organ of Corti.

Specimen 4O: embryonic day 17.5 (more )
Structure Cell Type Level Pattern Image Note
TS25: greater epithelial ridge Present 4O
TS25: organ of Corti supporting cell of cochlea Present 4O

Specimen 5D: embryonic day 14.0; Eya1bor/Eya1+ (more )
Structure Level Pattern Image Note
TS22: cochlea epithelium Present Regionally restricted 5D Expressed in the prosensory domain.

Specimen 5E: embryonic day 14.0; Eya1tm1Rilm/Eya1+ (more )
Structure Level Pattern Image Note
TS22: cochlea epithelium Present Regionally restricted 5E Expressed in the prosensory domain.

Specimen 5F: embryonic day 14.0; Eya1bor/Eya1bor (more )
Structure Level Pattern Image Note
TS22: cochlea epithelium Present Diffuse 5F Expression domain appeared to be diffused and not as sharply defined as in controls.

Specimen 5M: embryonic day 18.5; Eya1bor/Eya1+ (more )
Structure Cell Type Level Pattern Image Note
TS26: organ of Corti supporting cell of cochlea Present 5M
TS26: greater epithelial ridge border cell of cochlea Present 5M

Specimen 5N: embryonic day 18.5; Eya1tm1Rilm/Eya1+ (more )
Structure Cell Type Level Pattern Image Note
TS26: organ of Corti supporting cell of cochlea Present 5N
TS26: greater epithelial ridge border cell of cochlea Present 5N

Specimen 5O: embryonic day 18.5; Eya1bor/Eya1bor (more )
Structure Level Pattern Image Note
TS26: greater epithelial ridge Present 5O Disorganized expression pattern.
TS26: organ of Corti Present 5O Disorganized expression pattern.

Specimen not shown: embryonic day 15.5 (more )
Structure Cell Type Level Pattern Image Note
TS23: vestibular component epithelium supporting cell of vestibular epithelium Strong

Specimen not shown: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: cochlea epithelium Present Expressed in a broad group of cells in the less mature apical region throughout the thickness of the epithelium including the site of the future organ of Corti, and overlapped with Eya1 domain.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
09/17/2024
MGI 6.24
The Jackson Laboratory