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Wt1tm2.1(cre/ERT2)Wtp
Targeted Allele Detail
Summary
Symbol: Wt1tm2.1(cre/ERT2)Wtp
Name: WT1 transcription factor; targeted mutation 2.1, William T Pu
MGI ID: MGI:7528785
Gene: Wt1  Location: Chr2:104956874-105003959 bp, + strand  Genetic Position: Chr2, 55.06 cM, cytoband E
Alliance: Wt1tm2.1(cre/ERT2)Wtp page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:237690
Parent Cell Line:  J1 (ES Cell)
Strain of Origin:  129S4/SvJae
Mutation
description
Allele Type:    Targeted (Inducible, Recombinase)
Inducer:    tamoxifen
Mutation:    Insertion
 
Wt1tm2.1(cre/ERT2)Wtp expression driven by 1 gene
 
Mutation details: Exon 1 was replaced with an inducible cre ESR1 (ERT2) fusion followed by an FRT-flanked neo cassette. Flp-mediated recombination removed the selection cassette. (J:137426, J:237690)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Wt1 (mouse)
Summary of all recombinase alleles driven by Wt1.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Wt1 Mutation:  34 strains or lines available
References
Original:  J:237690 Da Costa CR, Deletion of FRT-flanked neo cassette from Grem1tm1Ecan. Personal Communication. 2016;
All:  2 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory