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Scgb3a2em1(dre/ERT2)Brst
Endonuclease-mediated Allele Detail
Summary
Symbol: Scgb3a2em1(dre/ERT2)Brst
Name: secretoglobin, family 3A, member 2; endonuclease-mediated mutation 1, Barry R Stripp
MGI ID: MGI:7531065
Synonyms: Scgb3a2-DreER
Gene: Scgb3a2  Location: Chr18:43897354-43900464 bp, + strand  Genetic Position: Chr18, 23.49 cM, cytoband C-D
Alliance: Scgb3a2em1(dre/ERT2)Brst page
Mutation
origin
Strain of Origin:  C57BL/6J
Mutation
description
Allele Type:    Endonuclease-mediated (Inducible, Recombinase)
Inducer:    tamoxifen
Mutation:    Insertion
 
Scgb3a2em1(dre/ERT2)Brst expression driven by 1 gene
 
Mutation details: Using a CRISPR/Cas9 knock-in strategy, an IRES-DreERT2 construct was inserted into the 3 UTR of the mouse Scgb3a2 gene. (J:340765)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Scgb3a2 (mouse)
Summary of all recombinase alleles driven by Scgb3a2.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Scgb3a2 Mutation:  13 strains or lines available
References
Original:  J:340765 Beppu AK, et al., Epithelial plasticity and innate immune activation promote lung tissue remodeling following respiratory viral infection. Nat Commun. 2023 Sep 19;14(1):5814
All:  1 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory