Shroom3 RNA in situ Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:293794 Durbin MD, et al., SHROOM3 is downstream of the planar cell polarity pathway and loss-of-function results in congenital heart defects. Dev Biol. 2020 Aug 15;464(2):124-136
Assay type:	RNA in situ
MGI Accession ID:	MGI:7531362
Gene symbol:	Shroom3
Gene name:	shroom family member 3

Probe:	Shroom3 cDNA1
Probe preparation:	Antisense labelled with digoxigenin RNA

Results

1A ©

1C ©

Specimen 1A: embryonic day 9.5; Shroom3^{Gt(ROSA53)Sor}/Shroom3⁺ (more

)

Structure	Level	Pattern	Image	Note
TS15: fronto-nasal process	Present		1A
TS15: mesenchyme derived from lateral plate	Present	Regionally restricted	1A , 1C	Expression is seen in lateral and splanchnic mesoderm just dorsal to the cardiac outflow tract.
TS15: heart	Absent		1C , 1A

5F ©

Specimen 5F: embryonic day 11.5 (more

)

Structure	Level	Pattern	Image	Note
TS19: heart	Present		5F

5G ©

Specimen 5G: embryonic day 11.5; Dvl2^tm1.2Wds/Dvl2^tm1.2Wds (more

)

Structure	Level	Pattern	Image	Note
TS19: heart	Present		5G	Expression levels are reduced in the mutant.

5H ©

Specimen 5H: embryonic day 12.5 (more

)

Structure	Level	Pattern	Image	Note
TS20: heart	Present		5H

5I ©

Specimen 5I: embryonic day 12.5; Dvl2^tm1.2Wds/Dvl2^tm1.2Wds (more

)

Structure	Level	Pattern	Image	Note
TS20: heart	Present		5I	Expression levels are reduced in the mutant.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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