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Ucp1em1(cre)Chez
Endonuclease-mediated Allele Detail
Summary
Symbol: Ucp1em1(cre)Chez
Name: uncoupling protein 1 (mitochondrial, proton carrier); endonuclease-mediated mutation 1, Zheng Chen
MGI ID: MGI:7532766
Synonyms: Ucp1-iCre
Gene: Ucp1  Location: Chr8:84016981-84025081 bp, + strand  Genetic Position: Chr8, 39.65 cM
Alliance: Ucp1em1(cre)Chez page
Mutation
origin
Strain of Origin:  Not Applicable
Mutation
description
Allele Type:    Endonuclease-mediated (Recombinase)
Mutation:    Insertion
 
Ucp1em1(cre)Chez expression driven by 1 gene
 
Mutation details: An IRES-Cre was introduced between the coding sequence of exon 6 and the 3'UTR of the Ucp1 gene. To avoid disrupting the polyA signal of Ucp1 expression, a Neo cassette flanked by frt sites was inserted 300 bp downstream of the 3'UTR. (J:283206)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Ucp1 (mouse)
Summary of all recombinase alleles driven by Ucp1.
 

Expression
In Mice Carrying this Mutation: 2 RNA-Seq or microarray experiment(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Ucp1 Mutation:  51 strains or lines available
References
Original:  J:283206 Li L, et al., Brown adipocytes can display a mammary basal myoepithelial cell phenotype in vivo. Mol Metab. 2017 Oct;6(10):1198-1211
All:  3 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory