Gene Expression Data
Assay Details
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Assay
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Reference:
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J:266925
Kim ST, et al., The N-recognin UBR4 of the N-end rule pathway is targeted to and required for the biogenesis of the early endosome. J Cell Sci. 2018 Sep 10;131(17):jcs217646
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Assay type:
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Immunohistochemistry
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MGI Accession ID:
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MGI:7536907
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Gene symbol:
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Ubr4
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Gene name:
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ubiquitin protein ligase E3 component n-recognin 4
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Results
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Specimen
1B +/+:
embryonic day 9.5
(more  )
Specimen
1B +/+:
(close  )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 9.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS15: yolk sac endoderm |
Present |
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1B +/+ inset
,
1B +/+
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Prominent expression in yolk sac endoderm
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Specimen
1B UBR4-/-:
(close )
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Genetic Background:
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involves: 129P2/OlaHsd
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Mutant Allele(s):
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Ubr4tm1.1Ytkw/Ubr4tm1.1Ytkw
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Age:
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embryonic day 9.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS15: yolk sac |
Absent |
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1B UBR4-/- inset
,
1B UBR4-/-
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Specimen
1C UBR4:
embryonic day 9.5
(more )
Note: Double labeled: red - Ubr4; green - Eea1 (assay MGI:7536908).
Specimen
1C UBR4:
(close )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 9.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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Note:
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Double labeled: red - Ubr4; green - Eea1 (assay MGI:7536908).
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| Structure |
Level |
Pattern |
Image |
Note |
| TS15: yolk sac |
Present |
Punctate |
1C (merged)
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1C UBR4
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1C UBR4 Enlarged
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1C (merged) Enlarged
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Expression in cytosolic puncta colocalized with Eea1-expression early endosomes.
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Analysis Tools
