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Tg(Prox1-cre/ERT2)1Jscal
Transgene Detail
Summary
Symbol: Tg(Prox1-cre/ERT2)1Jscal
Name: transgene insertion 1, Joshua Scallan
MGI ID: MGI:7537333
Synonyms: Prox1CreERT2
Transgene: Tg(Prox1-cre/ERT2)1Jscal  Location: unknown  
Alliance: Tg(Prox1-cre/ERT2)1Jscal page
Transgene
origin
Strain of Origin:  Not Specified
Transgene
description
Transgene Type:    Transgenic (Inducible, Recombinase)
Inducer:    tamoxifen
Mutation:    Insertion
 
Tg(Prox1-cre/ERT2)1Jscal expression driven by 1 gene
 
Mutation detailsThe RP23-360I16 BAC clone was used to generate a transgene in which CreERT2 followed by an SV40 polyA stop sequence was inserted after the start codon in exon 2 of the Prox1 gene. Random transgenesis generated 4 founders and the highest efficiency founder (line1) was selected for propagation. (J:341378)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Prox1 (mouse)
Summary of all recombinase alleles driven by Prox1.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:341378 Iyer D, et al., eNOS Regulates Lymphatic Valve Specification by Controlling beta-Catenin Signaling During Embryogenesis in Mice. Arterioscler Thromb Vasc Biol. 2023 Sep 28;
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory