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Ntrk2tm1.1(cre/ERT2)Pern
Targeted Allele Detail
Summary
Symbol: Ntrk2tm1.1(cre/ERT2)Pern
Name: neurotrophic tyrosine kinase, receptor, type 2; targeted mutation 1.1, Patrik Ernfors
MGI ID: MGI:7539562
Synonyms: TrkB-CreERT2
Gene: Ntrk2  Location: Chr13:58954383-59281784 bp, + strand  Genetic Position: Chr13, 31.2 cM
Alliance: Ntrk2tm1.1(cre/ERT2)Pern page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:270955
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  C57BL/6N
Mutation
description
Allele Type:    Targeted (Inducible, Recombinase)
Inducer:    tamoxifen
Mutation:    Insertion
 
Ntrk2tm1.1(cre/ERT2)Pern expression driven by 1 gene
 
Mutation details: The targeting construct inserted the inducible cre fusion recombinase (cre/ERT2) into the 3'UTR. Flp-mediated recombination removed the selection cassette. (J:270955)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Ntrk2 (mouse)
Summary of all recombinase alleles driven by Ntrk2.
 

Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Ntrk2 Mutation:  66 strains or lines available
References
Original:  J:270955 Peng C, et al., Termination of cell-type specification gene programs by the miR-183 cluster determines the population sizes of low-threshold mechanosensitive neurons. Development. 2018 Sep 25;145(18):dev165613
All:  1 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory