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Robo3tm1.1(cre/ERT2)Ddg
Targeted Allele Detail
Summary
Symbol: Robo3tm1.1(cre/ERT2)Ddg
Name: roundabout guidance receptor 3; targeted mutation 1.1, David D Ginty
MGI ID: MGI:7539707
Synonyms: Robo3IRES-CreERT2
Gene: Robo3  Location: Chr9:37327341-37344730 bp, - strand  Genetic Position: Chr9, 20.76 cM, cytoband B
Alliance: Robo3tm1.1(cre/ERT2)Ddg page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:297417
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Conditional ready, Inducible, Recombinase)
Inducer:    tamoxifen
Mutation:    Insertion
 
Robo3tm1.1(cre/ERT2)Ddg expression driven by 1 gene
 
Mutation details: A 3XSTOPIRESCreERT2 cassette was introduced via homologous recombination into the first common coding exon that is shared by different splice variants of the Robo3 gene. The neomycin selection cassette was removed. (J:297417)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Robo3 (mouse)
Summary of all recombinase alleles driven by Robo3.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Robo3 Mutation:  76 strains or lines available
References
Original:  J:297417 Choi S, et al., Parallel ascending spinal pathways for affective touch and pain. Nature. 2020 Nov;587(7833):258-263
All:  2 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory