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Gpr83tm1.1(cre/ERT2)Ddg
Targeted Allele Detail
Summary
Symbol: Gpr83tm1.1(cre/ERT2)Ddg
Name: G protein-coupled receptor 83; targeted mutation 1.1, David D Ginty
MGI ID: MGI:7539709
Synonyms: Gpr83CreERT2
Gene: Gpr83  Location: Chr9:14771506-14782085 bp, + strand  Genetic Position: Chr9, 4.4 cM, cytoband A2-A3
Alliance: Gpr83tm1.1(cre/ERT2)Ddg page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:297417
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Inducible, Recombinase)
Inducer:    tamoxifen
Mutation:    Insertion
 
Gpr83tm1.1(cre/ERT2)Ddg expression driven by 1 gene
 
Mutation details: A Cre recombinase-estrogen receptor T2 (CreERT2) fusion cassettes were introduced via homologous recombination into the Gpr83 genes, replacing the first coding ATG. The neomycin selection cassette was removed by recombination. (J:297417)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Gpr83 (mouse)
Summary of all recombinase alleles driven by Gpr83.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Gpr83 Mutation:  26 strains or lines available
References
Original:  J:297417 Choi S, et al., Parallel ascending spinal pathways for affective touch and pain. Nature. 2020 Nov;587(7833):258-263
All:  2 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory