Bmpr1bem1.1(cre/ERT2)Ddg
Allele Detail
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| Symbol: |
Bmpr1bem1.1(cre/ERT2)Ddg |
| Name: |
bone morphogenetic protein receptor, type 1B; endonuclease-mediated mutation 1.1, David D Ginty |
| MGI ID: |
MGI:7540313 |
| Synonyms: |
Bmpr1bT2a-CreER |
| Gene: |
Bmpr1b Location: Chr3:141542897-141875186 bp, - strand Genetic Position: Chr3, 66.11 cM
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| Alliance: |
Bmpr1bem1.1(cre/ERT2)Ddg page
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| Germline Transmission: |
Earliest citation of germline transmission:
J:341426
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| Parent Cell Line: |
Not Specified (ES Cell)
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| Strain of Origin: |
Not Specified
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| Allele Type: |
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Not Applicable (Inducible, Recombinase) |
| Mutation: |
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Insertion
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Bmpr1bem1.1(cre/ERT2)Ddg expression driven by
1 gene
Knock-in expression driven by:
| Organism |
Driver Gene |
Note |
| mouse |
Bmpr1b (MGI:107191) |
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Mutation details: Using standard CRISPR-based homologous recombination techniques in embryonic stem (ES) cells, T2a-CreER and frt flanked neo cassette were inserted into the last exon of the Bmpr1b gene. Chimeras were generated by blastocyst injection and subsequent germline transmission was confirmed by tail PCR. The neo-selection cassette was excised using a Flp-deleter strain.
(J:341426)
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Activity: |
 Tissue activity of this recombinase allele
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Driver:
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Bmpr1b
(mouse)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Carrying any Bmpr1b Mutation: |
38 strains or lines available
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| Original: |
J:341426 Wolfson RL, et al., DRG afferents that mediate physiologic and pathologic mechanosensation from the distal colon. Cell. 2023 Aug 3;186(16):3368-3385.e18 |
| All: |
1 reference(s) |
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Analysis Tools
