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Calcatm3.1(flpo/DsRed)Rpa
Targeted Allele Detail
Summary
Symbol: Calcatm3.1(flpo/DsRed)Rpa
Name: calcitonin/calcitonin-related polypeptide, alpha; targeted mutation 3.1, Richard D Palmiter
MGI ID: MGI:7543592
Synonyms: CalcaFLPo:DsRed
Gene: Calca  Location: Chr7:114230713-114235592 bp, - strand  Genetic Position: Chr7, 59.99 cM
Alliance: Calcatm3.1(flpo/DsRed)Rpa page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:341719
Parent Cell Line:  G4 (ES Cell)
Strain of Origin:  (129S6/SvEvTac x C57BL/6NCrl)F1
Mutation
description
Allele Type:    Targeted (Null/knockout, Recombinase, Reporter)
Mutations:    Insertion, Intragenic deletion
 
Calcatm3.1(flpo/DsRed)Rpa expression driven by 1 gene
 
Mutation detailsA targeting construct inserted the FLPo-DsRed and loxP-flanked SV-Neo into the exon 2 of the Calca gene. The loxP-flanked neo cassette was removed by cre recombinase. (J:341719)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Calca (mouse)
Summary of all recombinase alleles driven by Calca.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Calca Mutation:  23 strains or lines available
References
Original:  J:341719 Arthurs JW, et al., Parabrachial tachykinin1-expressing neurons involved in state-dependent breathing control. Nat Commun. 2023 Feb 21;14(1):963
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory