Tg(Lum-cre/ERT2)#Xen
Transgene Detail
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| Symbol: |
Tg(Lum-cre/ERT2)#Xen |
| Name: |
transgene insertion, Taconic Biosciences |
| MGI ID: |
MGI:7545167 |
| Synonyms: |
Tg(Lum-CreERT2) |
| Transgene: |
Tg(Lum-cre/ERT2)#Xen Location: unknown
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| Alliance: |
Tg(Lum-cre/ERT2)#Xen page
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| Strain of Origin: |
Not Specified
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| Transgene Type: |
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Transgenic (Inducible, Recombinase) |
| Inducer: |
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tamoxifen |
| Mutation: |
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Insertion
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Tg(Lum-cre/ERT2)#Xen expression driven by
1 gene
Transgene expression driven by:
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Mutation details: A BAC clone containing the entire Lum gene, and where the endogenous translation initiation codon from the Lum gene was used to drive expression of CreERT2. The coding sequence in exon 2, as well as the splice donor site at the junction between exon 2 and intron 2 (50bp), was replaced with a cassette containing the open reading frame for CreERT2 and the Lum 3' untranslated region (UTR). A hGHpA (human Growth Hormone) polyadenylation signal was inserted 3 of the Lum 3UTR.
(J:342042)
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Activity: |
 Tissue activity of this recombinase allele
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Driver:
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Lum
(mouse)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Original: |
J:342042 Pietila R, et al., Molecular anatomy of adult mouse leptomeninges. Neuron. 2023 Sep 25; |
| All: |
1 reference(s) |
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Analysis Tools
