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Tcf21tm1(cre/ERT2)Cbet
Targeted Allele Detail
Summary
Symbol: Tcf21tm1(cre/ERT2)Cbet
Name: transcription factor 21; targeted mutation 1, Christer Betsholtz
MGI ID: MGI:7545172
Synonyms: Tcf21-P2ACreERT2
Gene: Tcf21  Location: Chr10:22693162-22696042 bp, - strand  Genetic Position: Chr10, 10.33 cM
Alliance: Tcf21tm1(cre/ERT2)Cbet page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:342042
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Epitope tag, Inducible, Recombinase)
Inducer:    tamoxifen
Mutation:    Insertion
 
Tcf21tm1(cre/ERT2)Cbet expression driven by 1 gene
 
Mutation details: The allele was generated by the insertion of a cDNA cassette encoding a V5-bio epitope tag, a P2A sequence, and CreERT2 immediately 5 of the endogenous stop codon of the Tcf21 gene in ES cells through homologous recombination, blastocyst injection and germline transmission. (J:342042)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Tcf21 (mouse)
Summary of all recombinase alleles driven by Tcf21.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Tcf21 Mutation:  16 strains or lines available
References
Original:  J:342042 Pietila R, et al., Molecular anatomy of adult mouse leptomeninges. Neuron. 2023 Sep 25;
All:  1 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
10/09/2024
MGI 6.24 		The Jackson Laboratory