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Gene Expression Data
Assay Details
Assay
Reference: J:342013 Ramachandran J, et al., The BAF chromatin complex component SMARCC1 does not mediate GLI transcriptional repression of Hedgehog target genes in limb buds. Dev Biol. 2023 Oct 5;504:128-136
Assay type: RNA in situ
MGI Accession ID: MGI:7545713
Gene symbol: Sox9
Gene name: SRY (sex determining region Y)-box 9
Probe: Sox9 probe
Probe preparation: labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 4A: embryonic day 12.5; Smarcc1tm2.1Rhs/Smarcc1+ (more )
Structure Level Pattern Image Note
TS20: forelimb digit Present 4A Expression in 5 distinct condensates
Specimen 4B: embryonic day 12.5; Smarcc1tm2.1Rhs/Smarcc1tm2.1Rhs, Tg(Prrx1-cre)1Cjt/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS20: forelimb Present Regionally restricted 4B Expression in variable numbers of abnormally patterned condensates.
Specimen 4C: embryonic day 12.5; Shhtm1Amc/Shhtm1Amc (more )
Structure Level Pattern Image Note
TS20: forelimb Present 4C
Specimen 4D: embryonic day 12.5; Shhtm1Amc/Shhtm1Amc, Smarcc1tm2.1Rhs/Smarcc1tm2.1Rhs, Tg(Prrx1-cre)1Cjt/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS20: forelimb Present 4D Expression indistinguishable from that of Shh-/-.
Specimen 4E: embryonic day 12.5; Smarcc1tm2.1Rhs/Smarcc1+ (more )
Structure Level Pattern Image Note
TS20: hindlimb digit Present 4E Expression in 5 distinct condensates
Specimen 4F: embryonic day 12.5; Smarcc1tm2.1Rhs/Smarcc1tm2.1Rhs, Tg(Prrx1-cre)1Cjt/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS20: hindlimb Present Regionally restricted 4F Expression in variable numbers of abnormally patterned condensates.
Specimen 4G: embryonic day 12.5; Shhtm1Amc/Shhtm1Amc (more )
Structure Level Pattern Image Note
TS20: hindlimb Present 4G
Specimen 4H: embryonic day 12.5; Shhtm1Amc/Shhtm1Amc, Smarcc1tm2.1Rhs/Smarcc1tm2.1Rhs, Tg(Prrx1-cre)1Cjt/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS20: hindlimb Present 4H Expression indistinguishable from that of Shh-/-.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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09/17/2024
MGI 6.24 		The Jackson Laboratory