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Gfraltm1(cre)Vwwt
Targeted Allele Detail
Summary
Symbol: Gfraltm1(cre)Vwwt
Name: GDNF family receptor alpha like; targeted mutation 1, Vicky Wang-Wei Tsai
MGI ID: MGI:7546840
Synonyms: Gfral-IRES-cre
Gene: Gfral  Location: Chr9:76071389-76120939 bp, - strand  Genetic Position: Chr9, 42.48 cM
Alliance: Gfraltm1(cre)Vwwt page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:341053
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Recombinase)
Mutation:    Insertion
 
Gfraltm1(cre)Vwwt expression driven by 1 gene
    The targeting construct introduced a cre recombinase gene. (J:341053)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Gfral (mouse)
Summary of all recombinase alleles driven by Gfral.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Gfral Mutation:  36 strains or lines available
References
Original:  J:341053 Breit SN, et al., GDF15 enhances body weight and adiposity reduction in obese mice by leveraging the leptin pathway. Cell Metab. 2023 Aug 8;35(8):1341-1355.e3
All:  1 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory