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Msi2tm1.1(cre/ERT2)Reya
Targeted Allele Detail
Summary
Symbol: Msi2tm1.1(cre/ERT2)Reya
Name: musashi RNA-binding protein 2; targeted mutation 1.1, Tannishtha Reya
MGI ID: MGI:7548734
Synonyms: Msi2CreERT2
Gene: Msi2  Location: Chr11:88230208-88609197 bp, - strand  Genetic Position: Chr11, 52.4 cM, cytoband B5-C
Alliance: Msi2tm1.1(cre/ERT2)Reya page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:342146
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Inducible, Recombinase)
Inducer:    tamoxifen
Mutation:    Insertion
 
Msi2tm1.1(cre/ERT2)Reya expression driven by 1 gene
 
Mutation details: A CreERT2-cassette was integrated into the start codon of the Msi2 locus exon1 via homologous recombination in ES cells. (J:342146)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Msi2 (mouse)
Summary of all recombinase alleles driven by Msi2.
 

Tumor Data
List all tumor models in MMHCdb carrying Msi2tm1.1(cre/ERT2)Reya
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Msi2 Mutation:  781 strains or lines available
References
Original:  J:342146 Rajbhandari N, et al., Single-cell mapping identifies MSI(+) cells as a common origin for diverse subtypes of pancreatic cancer. Cancer Cell. 2023 Sep 25;
All:  1 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory