Slc18a3 RNA in situ Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:67383 Britsch S, et al., The transcription factor Sox10 is a key regulator of peripheral glial development. Genes Dev. 2001 Jan 1;15(1):66-78
Assay type:	RNA in situ
MGI Accession ID:	MGI:7569242
Gene symbol:	Slc18a3
Gene name:	solute carrier family 18 (vesicular monoamine), member 3

Probe:	pVAT2B
Probe preparation:	Antisense RNA

Results

6a ©

Specimen 6a: embryonic day 18.5 (more

)
Note: Quantified in Fig 6d.

Structure	Cell Type	Level	Pattern	Image	Note
TS26: spinal cord cervical region	spinal cord motor neuron	Present		6a

6b ©

Specimen 6b: embryonic day 18.5; Sox10^Dom/Sox10^Dom (more

)
Note: Quantified in Fig 6d.

Structure	Cell Type	Level	Pattern	Image	Note
TS26: spinal cord cervical region	spinal cord motor neuron	Present		6b	A very significant loss compared with the wild-type.

Specimen not shown: embryonic day 18.5; Erbb3^tm2Cbm/Erbb3^tm2Cbm (more

)
Note: Quantified in Fig 6d.

Structure	Cell Type	Level	Note
TS26: spinal cord cervical region	spinal cord motor neuron	Present	A very significant loss (similar extent as in Sox10 mutants) compared with the wild-type.
TS26: spinal cord lumbar region	spinal cord motor neuron	Present	A very significant loss (similar extent as in Sox10 mutants) compared with the wild-type.
TS26: spinal cord thoracic region	spinal cord motor neuron	Present	Similar as in the wild-type.

Specimen not shown: embryonic day 15.5 (more

)
Note: Quantified in Fig 6c.

Structure	Cell Type	Level
TS23: spinal cord cervical region	spinal cord motor neuron	Present
TS23: spinal cord lumbar region	spinal cord motor neuron	Present
TS23: spinal cord thoracic region	spinal cord motor neuron	Present

Specimen not shown: embryonic day 15.5; Sox10^Dom/Sox10^Dom (more

)
Note: Quantified in Fig 6c.

Structure	Cell Type	Level	Note
TS23: spinal cord lumbar region	spinal cord motor neuron	Present	Similar as in the wild-type.
TS23: spinal cord thoracic region	spinal cord motor neuron	Present	Similar as in the wild-type.
TS23: spinal cord cervical region	spinal cord motor neuron	Present	Somewhat reduced numbers compared with the wild-type.

Specimen not shown: embryonic day 15.5; Erbb3^tm2Cbm/Erbb3^tm2Cbm (more

)
Note: Quantified in Fig 6c.

Structure	Cell Type	Level	Note
TS23: spinal cord lumbar region	spinal cord motor neuron	Present	Similar as in the wild-type.
TS23: spinal cord thoracic region	spinal cord motor neuron	Present	Similar as in the wild-type.
TS23: spinal cord cervical region	spinal cord motor neuron	Present	Somewhat reduced numbers compared with the wild-type.

Specimen not shown: embryonic day 18.5 (more

)
Note: Quantified in Fig 6d.

Structure	Cell Type	Level	Pattern	Image	Note
TS26: spinal cord lumbar region	spinal cord motor neuron	Present
TS26: spinal cord thoracic region	spinal cord motor neuron	Present

Specimen not shown: embryonic day 18.5; Sox10^Dom/Sox10^Dom (more

)
Note: Quantified in Fig 6d.

Structure	Cell Type	Level	Pattern	Image	Note
TS26: spinal cord thoracic region	spinal cord motor neuron	Present			Similar as in the wild-type.
TS26: spinal cord lumbar region	spinal cord motor neuron	Present			A very significant loss (similar extent as in Erbb3 mutants) compared with the wild-type.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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