About   Help   FAQ
Igs2em1(Myh6-icre)Cya
Endonuclease-mediated Allele Detail
Summary
Symbol: Igs2em1(Myh6-icre)Cya
Name: intergenic site 2; endonuclease-mediated mutation 1, Cyagen Biosciences
MGI ID: MGI:7571622
Synonyms: alphaMHC-cre, H11-Myh6-iCre
Gene: Igs2  Location: unknown  Genetic Position: Chr11, Syntenic
Alliance: Igs2em1(Myh6-icre)Cya page
Mutation
origin
Strain of Origin:  C57BL/6J
Mutation
description
Allele Type:    Endonuclease-mediated (Recombinase)
Mutation:    Insertion
 
Igs2em1(Myh6-icre)Cya expression driven by 1 gene
 
Mutation detailsCRISPR-targeting introduced the mouse Myh6 promoter driving expression of an improved cre recombinase gene (icre). (J:343974)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Myh6 (mouse)
Summary of all recombinase alleles driven by Myh6.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Igs2 Mutation:  72 strains or lines available
References
Original:  J:343974 Yang J, et al., Mitochondria-associated membrane protein PACS2 maintains right cardiac function in hypobaric hypoxia. iScience. 2023 Apr 21;26(4):106328
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
08/02/2024
MGI 6.24
The Jackson Laboratory