Gt(ROSA)26Sortm1.1(CAG-CCre,-NCre)Syao
Targeted Allele Detail
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| Symbol: |
Gt(ROSA)26Sortm1.1(CAG-CCre,-NCre)Syao |
| Name: |
gene trap ROSA 26, Philippe Soriano; targeted mutation 1.1, Shenqin Yao |
| MGI ID: |
MGI:7573052 |
| Synonyms: |
RCL-CreV |
| Gene: |
Gt(ROSA)26Sor Location: Chr6:113044389-113054205 bp, - strand Genetic Position: Chr6, 52.73 cM
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| Alliance: |
Gt(ROSA)26Sortm1.1(CAG-CCre,-NCre)Syao page
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| Allele Type: |
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Targeted (Conditional ready, Inducible, Recombinase) |
| Mutation: |
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Insertion
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Gt(ROSA)26Sortm1.1(CAG-CCre,-NCre)Syao expression driven by
1 gene
Knock-in expression driven by:
| Organism |
Driver Gene |
Note |
| chicken |
CAG |
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Mutation details: The targeting vector is designed with (from 5' to 3') a ubiquitously expressed CAG (CMV enhancer/chicken beta-actin) promoter, a floxed STOP cassette (containing polyadenylation [pA] sites), CreV, a woodchuck hepatitis virus post-transcriptional regulatory element (WPRE; to enhance the mRNA transcript stability), a BGH polyA, an attB site, a PGK-Neo cassette with a PGK poly(A), and an attP site. CreV consists of a split, light-inducible Cre, with the N-terminal CreV (NCreV) and C-terminal CreV (CCreV) protein sequences separated by an internal ribosome entry site. PhiC31o-mediated recombination removed the neo cassette.
(J:101977)
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Activity: |
 Tissue activity of this recombinase allele
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Driver:
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CAG
(chicken)
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| Original: |
J:101977 The Jackson Laboratory, Information obtained from The Jackson Laboratory, Bar Harbor, ME. Unpublished. 2005-2017; |
| All: |
1 reference(s) |
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Analysis Tools
