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Thrbtm4(cre)Df
Targeted Allele Detail
Summary
Symbol: Thrbtm4(cre)Df
Name: thyroid hormone receptor beta; targeted mutation 4, Douglas Forrest
MGI ID: MGI:7587750
Synonyms: Thrbb2cre
Gene: Thrb  Location: Chr14:4431611-4809435 bp, - strand  Genetic Position: Chr14, 7.08 cM, cytoband A3
Alliance: Thrbtm4(cre)Df page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:345089
Parent Cell Line:  W9.5/W95 (ES Cell)
Strain of Origin:  129S1/Sv-Oca2+ Tyr+ Kitl+
Mutation
description
Allele Type:    Targeted (Null/knockout, Recombinase)
Mutations:    Insertion, Intragenic deletion
 
Thrbtm4(cre)Df expression driven by 1 gene
    A Cre cassette and a self-excising neomycin resistance gene replaced the gene coding sequences. (J:345089)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Thrb (mouse)
Summary of all recombinase alleles driven by Thrb.
 

Expression
In Mice Carrying this Mutation: 1 RNA-Seq or microarray experiment(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Thrb Mutation:  41 strains or lines available
References
Original:  J:345089 Aramaki M, et al., Transcriptional control of cone photoreceptor diversity by a thyroid hormone receptor. Proc Natl Acad Sci U S A. 2022 Dec 6;119(49):e2209884119
All:  2 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/17/2024
MGI 6.24 		The Jackson Laboratory