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Tg(Sox2-flpo)4.2.28Mhem
Transgene Detail
Summary
Symbol: Tg(Sox2-flpo)4.2.28Mhem
Name: transgene insertion 4.2.28, Myriam Hemberger
MGI ID: MGI:7587778
Synonyms: Sox2-Flp, Sox2-FlpO
Transgene: Tg(Sox2-flpo)4.2.28Mhem  Location: unknown  
Alliance: Tg(Sox2-flpo)4.2.28Mhem page
Transgene
origin
Strain of Origin:  DBA x C57BL/6
Transgene
description
Transgene Type:    Transgenic (Recombinase)
Mutation:    Insertion
 
Tg(Sox2-flpo)4.2.28Mhem expression driven by 1 gene
 
Mutation details: This transgene expresses FlpO recombinase under the control of a mouse Sox2 promoter contained in a ~13.7 kb genomic fragment encompassing the Sox2. Two founder lines (1.27 and 4.2.28) were established and used in further study. (J:333799)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Sox2 (mouse)
Summary of all recombinase alleles driven by Sox2.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:333799 Radford BN, et al., Defects in placental syncytiotrophoblast cells are a common cause of developmental heart disease. Nat Commun. 2023 Mar 1;14(1):1174
All:  1 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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11/19/2024
MGI 6.24 		The Jackson Laboratory