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Gene Expression Data
Assay Details
Assay
Reference: J:233142 Hilton MJ, et al., Notch signaling maintains bone marrow mesenchymal progenitors by suppressing osteoblast differentiation. Nat Med. 2008 Mar;14(3):306-14
Assay type: Western blot
MGI Accession ID: MGI:7593681
Gene symbol: Notch1
Gene name: notch 1
Antibody: anti-mN1A
Results Image: 6a N1
 Sample Information Bands Other Sample Information
Lane AgeStructure Size Not Specified (a) Genetic BackgroundMutant Allele(s)Sex Note
WT P w 8 TS28: femur
TS28: tibia
Present involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * SJL/J Notch1tm2Rko/Notch1tm2Rko, Notch2tm3Grid/Notch2tm3GridNot Specified
PNN P w 8 TS28: femur
TS28: tibia
Present (b) involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * SJL/J Notch1tm2Rko/Notch1tm1Con, Notch2tm3Grid/Notch2tm3Grid, Tg(Prrx1-cre)1Cjt/0Not Specified Conditional mutant.
Notes:
(a) intracellular domain
(b) Reduced by about 60% compared with the control.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
09/17/2024
MGI 6.24
The Jackson Laboratory