About   Help   FAQ
Slc47a1em1(cre/ERT2)Jkpns
Endonuclease-mediated Allele Detail
Summary
Symbol: Slc47a1em1(cre/ERT2)Jkpns
Name: solute carrier family 47, member 1; endonuclease-mediated mutation 1, Jonathan Kipnis
MGI ID: MGI:7595999
Synonyms: Slc47a1-creERT2
Gene: Slc47a1  Location: Chr11:61234227-61269171 bp, - strand  Genetic Position: Chr11, 37.96 cM
Alliance: Slc47a1em1(cre/ERT2)Jkpns page
Mutation
origin
Strain of Origin:  C57BL/6J
Mutation
description
Allele Type:    Endonuclease-mediated (Inducible, Recombinase)
Inducer:    tamoxifen
Mutation:    Insertion
 
Slc47a1em1(cre/ERT2)Jkpns expression driven by 1 gene
 
Mutation details: Using CRISPR/Cas9 technology, a cre/ERT2 fusion gene with a P2A self-cleaving peptide were inserted between the exon 16 and the 3' UTR of the Slc47a1 gene. (J:345366)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Slc47a1 (mouse)
Summary of all recombinase alleles driven by Slc47a1.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Slc47a1 Mutation:  44 strains or lines available
References
Original:  J:345366 Smyth LCD, et al., Identification of direct connections between the dura and the brain. Nature. 2024 Feb 7;
All:  1 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory