Slc47a1<em1(cre/ERT2)Jkpns> Endonuclease-mediated Allele Detail MGI Mouse (MGI:7595999)

Slc47a1^{em1(cre/ERT2)Jkpns}
Endonuclease-mediated Allele Detail

Summary

Symbol:	Slc47a1^{em1(cre/ERT2)Jkpns}
Name:	solute carrier family 47, member 1; endonuclease-mediated mutation 1, Jonathan Kipnis
MGI ID:	MGI:7595999
Synonyms:	Slc47a1-creER^T2
Gene:	Slc47a1 Location: Chr11:61234227-61269171 bp, - strand Genetic Position: Chr11, 37.96 cM
Alliance:	Slc47a1^{em1(cre/ERT2)Jkpns} page

Mutation
origin

Strain of Origin:

C57BL/6J

Mutation
description

Allele Type:

Endonuclease-mediated (Inducible, Recombinase)

Inducer:

tamoxifen

Mutation:

Insertion

Slc47a1^{em1(cre/ERT2)Jkpns} expression driven by 1 gene

Mutation details: Using CRISPR/Cas9 technology, a cre/ERT2 fusion gene with a P2A self-cleaving peptide were inserted between the exon 16 and the 3' UTR of the Slc47a1 gene. (J:345366)

Recombinase
activity

Activity:	Tissue activity of this recombinase allele
Driver:	Slc47a1 (mouse) Summary of all recombinase alleles driven by Slc47a1. Alliance mouse Slc47a1 gene page

Find Mice (IMSR)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available Cell Lines: 0 lines available
Carrying any Slc47a1 Mutation:	44 strains or lines available

References

Original:	J:345366 Smyth LCD, et al., Identification of direct connections between the dura and the brain. Nature. 2024 Feb 7;
All:	1 reference(s)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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