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Gene Expression Data
Assay Details
Assay
Reference: J:193048 Wu L, et al., A systematic survey of carbonic anhydrase mRNA expression during Mammalian inner ear development. Dev Dyn. 2013 Mar;242(3):269-80
Assay type: RNA in situ
MGI Accession ID: MGI:7596104
Gene symbol: Car2
Gene name: carbonic anhydrase 2
Probe: Car2 cDNA
Probe preparation: Antisense RNA
Results
Specimen 2B: embryonic day 15.5 (more )
Structure Cell Type Level Pattern Image Note
TS23: cochlear duct mesenchyme Present Regionally restricted 2B Transcripts were expressed in mesenchymal cells adjacent to the stria vascularis, spiral limbus, and basilar membrane.
TS23: greater epithelial ridge epithelial cell Weak 2B' , 2B
TS23: cochlear duct epithelium epithelial cell Weak Regionally restricted 2B , 2B' Weak expression was detected in epithelial cells in the outer sulcus.
TS23: vestibular component mesenchyme Weak Widespread 2B Weak and broad expression was detected in mesenchymal tissues surrounding the sensory organs.

Specimen 2D: postnatal day 21 (more )
Structure Cell Type Level Pattern Image Note
TS28: cochlea type 2 otic fibrocyte Strong 2D' , 2D
TS28: cochlea type 4 otic fibrocyte Strong 2D' , 2D
TS28: bony otic capsule Strong Regionally restricted 2D' , 2D Expression was detected in bone marrow.
TS28: cochlea type 1 otic fibrocyte Weak 2D , 2D'
TS28: stria vascularis Weak Regionally restricted 2D' , 2D Weak expression was observed in the apical and basal margins of stria vascularis.
TS28: organ of Corti cochlear outer hair cell Weak 2D , 2D'

Specimen 2E: postnatal day 5 (more )
Structure Cell Type Level Pattern Image Note
TS28: inner ear Present Widespread 2E Broad expression continued during neonatal development.
TS28: cochlea otic fibrocyte Weak 2E
TS28: basilar membrane Weak 2E
TS28: internal spiral sulcus Weak 2E
TS28: otic capsule Weak 2E
TS28: stria vascularis Weak 2E


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
09/17/2024
MGI 6.24
The Jackson Laboratory