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Gene Expression Data
Assay Details
Assay
Reference: J:197030 Stahl R, et al., Trnp1 regulates expansion and folding of the mammalian cerebral cortex by control of radial glial fate. Cell. 2013 Apr 25;153(3):535-49
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7611744
Gene symbol: Trnp1
Gene name: TMF1-regulated nuclear protein 1
Antibody: anti-Trnp1
Results
Specimen 1A: embryonic day 14.5 (more )
Structure Cell Type Level Pattern Image Note
TS22: cerebral cortex ventricular layer neural progenitor cell Present Regionally restricted 1A Expression localized to nucleus in apical progenitors in ventricular neurons.
TS22: cortical plate neuron Present Regionally restricted 1A Expression in newborn neurons in cortical plate.

Specimen 1B: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: telencephalon ventricular layer Present 1B Expression in virtually all cells in ventricular zone at E10.

Specimen 1C: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: cerebral cortex ventricular layer Present 1C Expression decreased significantly during development.

Specimen 1D: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: cerebral cortex ventricular layer Present 1D Expression decreased significantly during development.

Specimen 1E: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: cerebral cortex ventricular layer Present 1E Expression decreased significantly during development.

Specimen 1F: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: cerebral cortex ventricular layer Absent 1F No detectable expression at E18.

Specimen 1G: postnatal day 2 (more )
Structure Level Pattern Image Note
TS27: cerebral cortex Present 1G

Specimen 1H: postnatal day 6 (more )
Structure Level Pattern Image Note
TS28: cerebral cortex Trace 1H Expression vanished within the first postnatal week.

Specimen 1I: postnatal adult (more )
Structure Level Pattern Image Note
TS28: telencephalon subventricular zone Present 1I Expression in subependymal zone of lateral ventricle

Specimen 1I OB: postnatal adult (more )
Structure Level Pattern Image Note
TS28: main olfactory bulb Present 1I OB

Specimen 1I SEZ: postnatal adult (more )
Structure Level Pattern Image Note
TS28: telencephalon subventricular zone Present Regionally restricted 1I SEZ Expression in subependymal zone of lateral ventricle

Specimen 1J: embryonic day 14.5 (more )
Note: Double labeled: red - Trnp1; green - Pax6 (assay MGI:7611745).
Structure Level Pattern Image Note
TS22: cerebral cortex ventricular layer Present Regionally restricted 1J Higher expression in subpopulation of Pax6-expressing radial glia

Specimen 1J': embryonic day 14.5 (more )
Note: Double labeled: red - Trnp1; green - Pax6 (assay MGI:7611745).
Structure Cell Type Level Pattern Image Note
TS22: cerebral cortex ventricular layer radial glial cell Present Regionally restricted 1J' Higher expression in subpopulation of Pax6-expressing radial glia

Specimen 1K: embryonic day 14.5 (more )
Note: Double labeled: red - Trnp1; green - Eomes (assay MGI:7611746).
Structure Cell Type Level Pattern Image Note
TS22: cerebral cortex subventricular zone neural progenitor cell Trace 1K Expression largely absent in Tbr2-expressing basal progenitors.

Specimen 1K': embryonic day 14.5 (more )
Note: Double labeled: red - Trnp1; green - Eomes (assay MGI:7611746).
Structure Cell Type Level Pattern Image Note
TS22: cerebral cortex subventricular zone neural progenitor cell Trace 1K' Expression largely absent in Tbr2-expressing basal progenitors.

Specimen 1L: embryonic day 14.5 (more )
Note: Double labeled: red - Trnp1; green - Tbr1 (assay MGI:7611747).
Structure Cell Type Level Pattern Image Note
TS22: cerebral cortex neuron Present Regionally restricted 1L Expression in subpopulation of Tbr1-expressing neurons.

Specimen 1L': embryonic day 14.5 (more )
Note: Double labeled: red - Trnp1; green - Tbr1 (assay MGI:7611747).
Structure Cell Type Level Pattern Image Note
TS22: cerebral cortex neuron Present Regionally restricted 1L' Expression in subpopulation of Tbr1-expressing neurons.

Specimen S1D Control: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: brain Present S1D Control Trnp1 , S1D Control DAPI/Trnp1

Specimen S1E SEZ: postnatal adult (more )
Structure Level Pattern Image Note
TS28: cerebral cortex subventricular zone Present S1E SEZ DAPI/Trnp1 , S1E SEZ Trnp1

Specimen S1E RMS: postnatal adult (more )
Structure Level Pattern Image Note
TS28: rostral migratory stream Present S1E RMS Trnp1 , S1E RMS DAPI/Trnp1

Specimen S1E OB GL: postnatal adult (more )
Structure Level Pattern Image Note
TS28: main olfactory bulb glomerular layer Present S1E OB GL DAPI/Trnp1 , S1E OB GL Trnp1

Specimen S1E OB GCL: postnatal adult (more )
Structure Level Pattern Image Note
TS28: main olfactory bulb granule cell layer Present S1E OB GCL Trnp1 , S1E OB GCL DAPI/Trnp1

Specimen S1F Dcx/Trnp1: postnatal adult (more )
Note: Double labeled: red - Trnp1; green - Dcx (assay MGI:7611748).
Structure Level Pattern Image Note
TS28: rostral migratory stream Present S1F Dcx/Trnp1 , S1F Trnp1
TS28: telencephalon subventricular zone Present S1F Dcx/Trnp1 , S1F Trnp1

Specimen S1G Dcx/Trnp1: postnatal adult (more )
Note: Double labeled: red - Trnp1; green - Dcx (assay MGI:7611748).
Structure Level Pattern Image Note
TS28: telencephalon subventricular zone Present S1G Dcx/Trnp1/DAPI , S1G Dcx/Trnp1

Specimen S1G BrdU/Trnp1: postnatal adult (more )
Note: Double labeled: red - Trnp1; green - BrdU.
Structure Level Pattern Image Note
TS28: telencephalon subventricular zone Present S1G BrdU/Trnp1/DAPI , S1G BrdU/Trnp1

Specimen S1H: postnatal adult (more )
Structure Level Pattern Image Note
TS28: dentate gyrus Absent S1H Trnp1 , S1H Trnp2/DAPI


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory